1. Randomise game
2. Game difficulty
#1 is impossible, because you'd lose all the clues to where things are. You need the dialogue to synch up with where things are. If you could limit this to things like minerals and non-essential systems, then it would be workable, but you can't really change anything that would muck up the dialogue or the ability to get through the game without guessing what needs to be done (i.e. where to go).
#2 is very possible however...unfortunately there's been no agreement in that, for the gaming purists and so forth, like the ones that already complain that the game is too hard as it is or the ones that don't want anything changed.