Mycon vs Syreen is HARDLY an even fight. Not impossible, but hardly even either.
Favoring who? Who'd win? (in your opinion.) I've always had a problem with the combo because the plasmoids are too slow to catch a syreen, but the syreen is too slow to get around them, plus if she gets close enough to draw out crew or shoot they mycon generally has enough time to regenerate.
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The Syreen has a strong edge, if the captain has figured out how to get the Mycon into immediate range. This is a bit of a trick, but there are ways. Note that the Mycon are actually at a disadvantage if they slingshot for extra speed, since this means the syreen can loop around and get close from a direction it is unsafe for the mycon to retaliate in.